Both are commonly described as “ketamine therapy,” but they can differ substantially in route, treatment environment, cost structure, and clinical support.
| At-home ketamine | IV ketamine | |
|---|---|---|
| Where treatment occurs | At home after evaluation and prescription by a participating clinician. | In a medical clinic with intravenous administration. |
| Price structure | Often subscription or program pricing. Joyous currently advertises plans starting at $129/month. | Often per-infusion pricing. Ketamine Compass has reviewed NYC examples around $500 to $550 per infusion. |
| Insurance | Varies by program; Joyous states its treatment and consultations are not covered. | Psychiatric IV ketamine is commonly self-pay, though reimbursement pathways can vary. |
| Monitoring | Remote program structure and instructions vary by provider. | On-site clinical monitoring during treatment. |
| Therapy | Ranges from digital resources to therapist-supported KAP models. | Ranges from medical-only infusion care to coordinated therapy/integration. |
Example at-home source: Joyous pricing. NYC IV provider examples: Keta Medical Center · NY Ketamine Infusions.
Someone who values convenience may rank at-home care higher. Someone who values in-person monitoring may rank an IV clinic higher. Someone who strongly prefers insurance may want to investigate Spravato instead of assuming either ketamine model will be covered.
Some at-home programs publish lower recurring prices than NYC IV clinics, but the treatment models and included services are different.
Coverage varies by program. Joyous currently states its ketamine treatment and consultations are not covered by insurance.
IV ketamine is administered in a clinic, so it inherently includes an in-person treatment environment. At-home programs use remote care models.
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